Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic Acidemia

Completed · Phase 2

Conditions studied: Lactic Acidosis

In brief

OBJECTIVES: I. Determine the pharmacokinetics of sodium dichloroacetate (DCA) in patients with congenital lactic acidemia. II. Determine the efficacy of DCA in decreasing the frequency and/or severity of acute episodes of acidotic illness, improving linear growth, improving neurological or developmental function, or slowing neurological or developmental deterioration in these patients.

Key facts

Study ID
NCT00004493
Run by
University of California, San Diego
People needed
75
Starts
1998-09-01
Expected to finish
2003-09-01
Last updated by the study team
2015-03-25

Who can join

Age: 0 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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