Bone Marrow Transplantation in Treating Children With Sickle Cell Disease

Completed · Phase 1/Phase 2

Conditions studied: Sickle Cell Anemia

In brief

RATIONALE: Sickle cell disease is an inherited disorder in which abnormal, crescent-shaped red blood cells interfere with the ability of the blood to carry oxygen through the body and can cause severe pain, stroke, and organ damage. Bone marrow transplantation, is a procedure in which the soft, sponge-like tissue in the center of bones producing white blood cells, red blood cells, and platelets is replaced by bone marrow from a another person. Bone marrow transplantation may be an effective treatment in relieving the symptoms of sickle cell disease. PURPOSE: Phase I/II trial to study the effectiveness of bone marrow transplantation in treating children who have sickle cell disease.

Key facts

Study ID

NCT00004485

Run by

Fred Hutchinson Cancer Center

People needed

50

Starts

1999-12-01

Last updated by the study team

2008-09-10

Who can join

Age: any, up to 16. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Children's Hospital of Oakland — Oakland, California, United States
• Fred Hutchinson Cancer Research Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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