Phase III Randomized Study of Cyclophosphamide With or Without Antithymocyte Globulin Before Bone Marrow Transplantation in Patients With Aplastic Anemia

Completed · Phase 3

Conditions studied: Aplastic Anemia

In brief

OBJECTIVES: I. Compare outcome, including graft failure, graft versus host disease, and survival of HLA-identical sibling bone marrow transplants for aplastic anemia using cyclophosphamide with or without antithymocyte globulin as a conditioning regimen.

Key facts

Study ID

NCT00004474

Run by

Roswell Park Cancer Institute

People needed

224

Starts

1998-09-01

Expected to finish

2007-08-01

Last updated by the study team

2018-03-12

Who can join

Age: any, up to 59. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Roswell Park Cancer Institute — Buffalo, New York, United States
• University of Texas - MD Anderson Cancer Center — Houston, Texas, United States
• Medical College of Wisconsin — Milwaukee, Wisconsin, United States
• Midwest Children's Cancer Center — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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