Study of Fluoxetine in Patients With Depersonalization Disorder
Completed · Not applicable
Conditions studied: Depersonalization Disorder
In brief
The purpose of this study is to: 1\) Determine the effects of fluoxetine in the treatment of depersonalization disorder, 2) Assess the durability of treatment response in these patients, 3) Assess the improvement in psychiatric disability in these patients, and 4) Assess the effects of comorbid Axis I disorders (depression, social phobia, panic/anxiety, obsessive-compulsive disorder) and Axis II personality disorders on treatment outcome in these patients.
Key facts
- Study ID
- NCT00004446
- Run by
- National Institute of Mental Health (NIMH)
- People needed
- 80
- Starts
- 1998-04-01
- Last updated by the study team
- 2005-06-24
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- Prior or concurrent bio- or chemotherapy or
- Use of any of the following within 2 weeks prior to study entry: antipsychotics, anticonvulsants, stimulants, barbiturates, lithium, benzodiazepines, or antidepressants
- Use of MAO inhibitors or investigational drugs within 4 weeks prior to study entry
- History of fluoxetine use at a dose of 10 mg or more for at least 6 weeks duration
- Hematologic, hepatic, renal, cardiovascular, pulmonary, metabolic, endocrine, systemic, or gastrointestinal disease
- History of mental disorders
- Current substance abuse
- Current eating disorder
- Current clinically unstable suicidal ideation
- Unstable medical illness
- Clinically unstable
- Clinically important abnormalities in lab tests or physical exams
- History of seizure disorders or abnormal electroencephalogram
- Hypersensitivity or severe side effects to fluoxetine
- Pregnancy or breast-feeding. Women of child-bearing potential must use effective contraception
Where it is running
- Mount Sinai Medical Center, NY — New York, New York, United States
Full record on ClinicalTrials.gov
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