Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization

Completed · Not applicable

Conditions studied: Corneal Neovascularization

In brief

OBJECTIVES: I. Demonstrate the safety and efficacy of dihematoporphyrin derivative (DHP) in laser photodynamic therapy (PDT) in patients with corneal neovascularization. II. Document the histopathologic mechanism of action in selected patients undergoing penetrating keratoplasty following PDT therapy for corneal neovascularization. III. Facilitate FDA product approval of DHP as a photosensitizing agent for laser treatment in these patients. IV. Explore the use of this photosensitizer for ocular and cutaneous basal cell and squamous cell carcinoma.

Key facts

Study ID

NCT00004430

Run by

Medical College of Hampton Roads

People needed

150

Starts

1994-09-01

Expected to finish

1998-09-01

Last updated by the study team

2015-03-25

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Eastern Virginia Medical School — Norfolk, Virginia, United States

Full record on ClinicalTrials.gov

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