Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers
Completed · Phase 2
Conditions studied: Skin Ulcers, Sickle Cell Anemia
In brief
OBJECTIVES: I. Compare the efficacy of local care alone vs local care plus arginine butyrate in terms of healing rate in patients with refractory sickle cell ulcers. II. Determine the effect of arginine butyrate therapy on tissue factors related to promotion or inhibition of wound healing in these patients. III. Determine whether the regimen used in this study is appropriate for testing in pivotal trials.
Key facts
- Study ID
- NCT00004412
- Run by
- Susan P. Perrine
- People needed
- 23
- Starts
- 1997-09-01
- Expected to finish
- 2005-02-01
- Last updated by the study team
- 2015-03-31
Who can join
Age: 16 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Illinois College of Medicine — Chicago, Illinois, United States
- Boston University School of Medicine — Boston, Massachusetts, United States
- Mount Sinai School of Medicine — New York, New York, United States
- University of Tennessee, Memphis Cancer Center — Memphis, Tennessee, United States
Full record on ClinicalTrials.gov
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