Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis

Status unconfirmed · Phase 2

Conditions studied: Cerebrotendinous Xanthomatosis

In brief

OBJECTIVES: I. Assess the biosynthesis of cholesterol and cholestanol, and measure the turnover of individual sterols and bile acids in patients with cerebrotendinous xanthomatosis before and after a cholesterol- and cholestanol-free diet. II. Assess the biosynthesis of cholesterol and cholestanol, and measure the turnover of individual sterols and bile acids in these patients before and after lovastatin and chenodeoxycholic acid.

Key facts

Study ID

NCT00004346

Run by

National Center for Research Resources (NCRR)

People needed

5

Starts

1996-01-01

Last updated by the study team

2005-06-24

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Oregon Health and Science University — Portland, Oregon, United States (enrolling)

Full record on ClinicalTrials.gov

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