International Registry for Severe Chronic Neutropenia
Status unconfirmed
Conditions studied: Neutropenia
In brief
OBJECTIVES: I. Document the clinical course of severe chronic neutropenia (SCN). II. Monitor and assess long term safety of primary treatment in SCN patients in the United States, Canada, Europe, and Australia. III. Study the incidence and outcome of adverse events such as osteoporosis, splenomegaly, cytogenetic abnormalities, myelodysplastic syndrome, and leukemia. IV. Evaluate growth and development and hematologic parameters. V. Monitor for clinically significant changes in primary treatment response over time. VI. Establish a physician network to increase the understanding of SCN. VII. Establish a demographic database to allow for future research.
Key facts
- Study ID
- NCT00004342
- Run by
- National Center for Research Resources (NCRR)
- People needed
- 1000
- Starts
- 1994-06-01
- Last updated by the study team
- 2020-10-22
Who can join
Age: 0 and older. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- Neutropenia known to be drug induced
- Primary myelodysplasia
- Primary leukemia
- Aplastic anemia
- Known HIV disease
- Systemic autoimmune diseases such as rheumatoid arthritis or systemic lupus erythematosus
- Chemotherapy-induced neutropenia (within the last 5 years)
Where it is running
- Dana-Farber/Boston Children¹s Cancer and Blood Disorders Center — Boston, Massachusetts, United States (enrolling)
- University of Massachusetts — Worcester, Massachusetts, United States (enrolling)
- University of Michigan — Ann Arbor, Michigan, United States (enrolling)
- St. Joseph's Children's Hospital — Paterson, New Jersey, United States (enrolling)
- University of Washington School of Medicine — Seattle, Washington, United States (enrolling)
- Monash University — Melbourne, Victoria, Australia (enrolling)
- CancerCare Manitoba — Winnipeg, Manitoba, Canada (enrolling)
- Hospital for Sick Children — Toronto, Ontario, Canada (enrolling)
- Medizinische Hochschule Hannover — Hanover, Germany (enrolling)
- Leeds Teaching Hospitals, Yorkshire Regional Centre for Paediatric Oncology & Haematology — Leeds, England, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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