Study of Depression, Peptides, and Steroids in Cushing's Syndrome

Status unconfirmed

Conditions studied: Cushing's Syndrome

In brief

OBJECTIVES: I. Study the relationship between dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and disorders of mood, vegetative function, and cognition in patients with Cushing's disease. II. Identify subgroups of patients with Cushing's disease who differ in the presence and severity of the depressive syndrome, and uncover HPA axis dysregulation differences among them using corticotropin-releasing hormone, metyrapone, and dexamethasone challenge testing.

Key facts

Study ID

NCT00004334

Run by

National Center for Research Resources (NCRR)

People needed

8

Starts

1994-07-01

Last updated by the study team

2005-06-24

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Michigan Health Systems — Ann Arbor, Michigan, United States (enrolling)

Full record on ClinicalTrials.gov

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