Study of Alpha-2 Adrenergic Receptor Dysfunction in Regional Lipoatrophy

Completed

Conditions studied: Lipodystrophy

In brief

OBJECTIVES: I. Determine the response in plasma norepinephrine concentration and plasma glycerol to the agonist (clonidine) and the antagonist (yohimbine) of the alpha-2 adrenergic receptor in 6 patients with regional lipoatrophy and in 6 controls. II. Determine the full sequence of the alpha-2 adrenergic receptor structural gene in genomic DNA from peripheral blood leukocytes.

Key facts

Study ID

NCT00004329

Run by

National Center for Research Resources (NCRR)

People needed

12

Starts

1999-11-01

Last updated by the study team

2005-06-24

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: accepted.

Where it is running

• University of Texas Medical Branch — Galveston, Texas, United States

Full record on ClinicalTrials.gov

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