Study of the Neurobiology of Tourette Syndrome and Related Disorders

Completed

Conditions studied: Tourette Syndrome, Obsessive Compulsive Disorder

In brief

OBJECTIVES: I. Investigate the pathobiology of Tourette syndrome and related disorders by measuring various compounds of interest in cerebrospinal fluid, plasma, and urine of patients with Tourette syndrome, obsessive compulsive disorder, and/or chronic tics. II. Determine the pattern of familial aggregation of Tourette syndrome and obsessive compulsive disorder by systematic assessment of all first-degree family members of patients selected for cerebrospinal fluid studies. III. Establish the neurochemical and neuropeptide profile associated with the range of expression of the putative Tourette gene expression in adult and adolescent patients.

Key facts

Study ID

NCT00004325

Run by

National Center for Research Resources (NCRR)

People needed

200

Starts

1988-12-01

Last updated by the study team

2005-06-24

Who can join

Age: 12 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Yale University School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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