Study of Treatment and Metabolism in Patients With Urea Cycle Disorders

Status unconfirmed · Phase 1

Conditions studied: Amino Acid Metabolism, Inborn Errors

In brief

RATIONALE: The urea cycle is the process in which nitrogen is removed from the blood and converted into urea, a waste product found in urine . Urea cycle disorders are inherited disorders caused by the lack of an enzyme that removes ammonia from the bloodstream. Gene therapy is treatment given to change a gene so that it functions normally. Studying the treatment and metabolism of patients with urea cycle disorders may be helpful in developing new treatments for these disorders. PURPOSE: Two-part clinical trial to study the treatment and metabolism of patients who have urea cycle disorders.

Key facts

Study ID

NCT00004307

Run by

National Center for Research Resources (NCRR)

People needed

66

Starts

1999-12-01

Last updated by the study team

2005-06-24

Who can join

Age: 1 and older, up to 64. Sex: any. Healthy volunteers: accepted.

Where it is running

• Baylor College of Medicine — Houston, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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