Drugs for High Blood Pressure and High Cholesterol in American Indians With Type 2 Diabetes

Completed · Phase 3

Conditions studied: Diabetic Nephropathy

In brief

OBJECTIVES: I. Establish a long-term working relationship between clinical investigators and the Minnesota American Indian community. II. Compare the effectiveness of lisinopril (an angiotensin-converting enzyme inhibitor) and nifedipine (a calcium channel blocker) in preventing nephropathy and vascular disease in Minnesota American Indians with non-insulin-dependent diabetes mellitus and microalbuminuria. III. Compare the effectiveness of simvastatin (a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor) with lipid-lowering strategies recommended by the National Cholesterol Education Program in preventing nephropathy and vascular diseases in these patients.

Key facts

Study ID
NCT00004266
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
People needed
160
Starts
1993-08-01
Expected to finish
1999-07-01
Last updated by the study team
2018-03-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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