Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantation
Completed · Phase 2/Phase 3
Conditions studied: Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes
In brief
RATIONALE: Bone marrow that has been treated to remove certain white blood cells may reduce the chance of developing graft-versus-host disease following bone marrow transplantation. PURPOSE: Randomized phase II/III trial to compare the effectiveness of treated bone marrow with that of untreated bone marrow in preventing graft-versus-host disease in patients with acute or chronic leukemia who are undergoing bone marrow transplantation.
Key facts
- Study ID
- NCT00004255
- Run by
- Chimeric Therapies
- Starts
- 2000-03-01
- Expected to finish
- 2003-05-01
- Last updated by the study team
- 2013-07-10
Who can join
Age: 12 and older, up to 50. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of California San Diego Cancer Center — La Jolla, California, United States
- Presbyterian-St Luke's Medical Center — Denver, Colorado, United States
- Lombardi Cancer Center — Washington D.C., District of Columbia, United States
- Shands Hospital and Clinics, University of Florida — Gainesville, Florida, United States
- Indiana Blood and Marrow Transplantation — Indianapolis, Indiana, United States
- James Graham Brown Cancer Center — Louisville, Kentucky, United States
- Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
- University of Rochester Cancer Center — Rochester, New York, United States
- New York Medical College — Valhalla, New York, United States
- University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
- Oregon Cancer Center — Portland, Oregon, United States
- Hahnemann University Hospital — Philadelphia, Pennsylvania, United States
- University of Texas - MD Anderson Cancer Center — Houston, Texas, United States
- South Texas Cancer Institute — San Antonio, Texas, United States
- Massey Cancer Center — Richmond, Virginia, United States
Full record on ClinicalTrials.gov
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