Leucovorin and Fluorouracil With or Without SU5416 in Treating Patients With Metastatic Colorectal Cancer

Completed · Phase 3

Conditions studied: Colorectal Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. SU5416 may stop the growth of colorectal cancer by stopping blood flow to the tumor. It is not yet known whether chemotherapy is more effective with or without SU5416 in treating metastatic colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of leucovorin and fluorouracil with or without SU5416 in treating patients who have metastatic colorectal cancer.

Key facts

Study ID

NCT00004252

Run by

Pfizer

Starts

1999-11-01

Expected to finish

2007-09-01

Last updated by the study team

2012-09-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Alabama Oncology, LLC — Montgomery, Alabama, United States
• Office of Richard Shapiro, Benjamin Stafford, and Sharon J. Yee — Arcadia, California, United States
• Scripps Clinic — La Jolla, California, United States
• Tower Hematology Oncology Medical Group — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• St. Francis Hospital — San Francisco, California, United States
• Comprehensive Cancer Care Specialists of Boca Raton — Boca Raton, Florida, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• Queen's Medical Center — Honolulu, Hawaii, United States
• Mary Bird Perkins Cancer Center — Baton Rouge, Louisiana, United States
• Johns Hopkins Oncology Center — Baltimore, Maryland, United States
• Cancer Center of Boston — Boston, Massachusetts, United States
• Michigan State University — East Lansing, Michigan, United States
• University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
• APN-IMPATH Research Corporation — Fort Lee, New Jersey, United States
• Hackensack University Medical Center — Hackensack, New Jersey, United States
• New York Medical College — Valhalla, New York, United States
• Presbyterian Healthcare — Charlotte, North Carolina, United States
• Raleigh Hematology/Oncology Associates - Wake Practice — Raleigh, North Carolina, United States
• Hematology/Oncology Associates of NE Pennsylvania, P.C. — Scranton, Pennsylvania, United States
• Associates in Oncology & Hematology — Chattanooga, Tennessee, United States
• Dial Research Associates, Inc. — Nashville, Tennessee, United States
• Presbyterian Hospital of Dallas — Dallas, Texas, United States
• University of Texas Medical Branch — Galveston, Texas, United States
• University of Texas - MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.