S9921, Hormone Therapy With or Without Mitoxantrone and Prednisone in Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer
Completed · Phase 3
Conditions studied: Prostate Cancer
In brief
RATIONALE: Hormones can stimulate the production of prostate cancer cells. Hormone therapy may fight prostate cancer by reducing the production of androgens. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether hormone therapy plus mitoxantrone and prednisone is more effective than hormone therapy alone for prostate cancer. PURPOSE: This randomized phase III trial is studying hormone therapy, mitoxantrone, and prednisone to see how well they work compared to hormone therapy alone in treating patients who have undergone radical prostatectomy for prostate cancer.
Key facts
- Study ID
- NCT00004124
- Run by
- SWOG Cancer Research Network
- People needed
- 983
- Starts
- 1999-10-15
- Expected to finish
- 2018-05-01
- Last updated by the study team
- 2022-12-30
Who can join
Age: 18 and older, up to 120. Sex: male. Healthy volunteers: not accepted.
Where it is running
- Providence Cancer Center — Anchorage, Alaska, United States
- Banner Thunderbird Medical Center — Glendale, Arizona, United States
- Banner Good Samaritan Medical Center — Phoenix, Arizona, United States
- CCOP - Western Regional, Arizona — Phoenix, Arizona, United States
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Highlands Oncology Group - Springdale — Springdale, Arkansas, United States
- Alta Bates Comprehensive Cancer Center — Berkeley, California, United States
- Peninsula Medical Center — Burlingame, California, United States
- California Cancer Care, Incorporated — Greenbrae, California, United States
- Marin Cancer Institute at Marin General Hospital — Greenbrae, California, United States
- Sutter Health - Western Division Cancer Research Group — Greenbrae, California, United States
- Naval Medical Center - San Diego — San Diego, California, United States
- San Francisco General Hospital Medical Center — San Francisco, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- California Pacific Medical Center - California Campus — San Francisco, California, United States
- Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
- Cancer Center of Santa Barbara — Santa Barbara, California, United States
- Sansum Medical Clinic — Santa Barbara, California, United States
- Santa Barbara Hematology Oncology Medical Group at Cancer Center of Santa Barbara — Santa Barbara, California, United States
- Santa Barbara Hematology Oncology - Solvang — Solvang, California, United States
- Sutter Solano Medical Center — Vallejo, California, United States
- Memorial Hospital — Colorado Springs, Colorado, United States
- North Colorado Medical Center — Greeley, Colorado, United States
- McKee Medical Center — Loveland, Colorado, United States
- Alaska Regional Hospital Cancer Center — Anchorage, Alaska, United States
Full record on ClinicalTrials.gov
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