SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma
Completed · Phase 3
Conditions studied: Lymphoma
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and radiation and kill more cancer cells. It is not yet known whether chemoradiotherapy plus peripheral stem cell transplantation is more effective than combination chemotherapy alone in treating non-Hodgkin's lymphoma. PURPOSE: This randomized phase III trial is studying chemoradiotherapy and peripheral stem cell transplantation to see how well they work compared to combination chemotherapy in treating patients with stage II, stage III, or stage IV non-Hodgkin's lymphoma.
Key facts
- Study ID
- NCT00004031
- Run by
- SWOG Cancer Research Network
- People needed
- 397
- Starts
- 1997-07-01
- Expected to finish
- 2013-10-31
- Last updated by the study team
- 2021-02-02
Who can join
Age: 15 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Oregon Health & Science University — Portland, Oregon, United States
- Tom Baker Cancer Centre - Calgary — Calgary, Alberta, Canada
- Cross Cancer Institute at University of Alberta — Edmonton, Alberta, Canada
- CancerCare Manitoba — Winnipeg, Manitoba, Canada
- Moncton Hospital — Moncton, New Brunswick, Canada
- Doctor H. Bliss Murphy Cancer Centre — St. John's, Newfoundland and Labrador, Canada
- Nova Scotia Cancer Centre — Halifax, Nova Scotia, Canada
- Margaret and Charles Juravinski Cancer Centre — Hamilton, Ontario, Canada
- London Regional Cancer Program at London Health Sciences Centre — London, Ontario, Canada
- Odette Cancer Centre at Sunnybrook — Toronto, Ontario, Canada
- Hopital Notre-Dame du CHUM — Montreal, Quebec, Canada
- Hopital Du Sacre-Coeur de Montreal — Montreal, Quebec, Canada
- Centre Hospitalier Universitaire de Quebec — Québec, Quebec, Canada
- Hopital du Saint-Sacrement - Quebec — Québec, Quebec, Canada
- Saskatoon Cancer Centre at the University of Saskatchewan — Saskatoon, Saskatchewan, Canada
Full record on ClinicalTrials.gov
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