S9916, Combination Therapy in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy
Completed · Phase 3
Conditions studied: Prostate Cancer
In brief
RATIONALE: Drugs used in chemotherapy and hormone therapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving drugs in different ways may kill more tumor cells. It is not yet known whether estramustine plus docetaxel is more effective than mitoxantrone plus prednisone for prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of estramustine plus docetaxel with that of mitoxantrone plus prednisone in treating patients who have stage IV prostate cancer that has not responded to hormone therapy.
Key facts
- Study ID
- NCT00004001
- Run by
- SWOG Cancer Research Network
- People needed
- 770
- Starts
- 1999-10-01
- Expected to finish
- 2007-01-01
- Last updated by the study team
- 2014-02-25
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- CCOP - Scottsdale Oncology Program — Scottsdale, Arizona, United States
- Mayo Clinic — Jacksonville, Florida, United States
- CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
- CCOP - Carle Cancer Center — Urbana, Illinois, United States
- CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
- CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
- Siouxland Hematology-Oncology — Sioux City, Iowa, United States
- Mayo Clinic Cancer Center — Rochester, Minnesota, United States
- CentraCare Health Plaza — Saint Cloud, Minnesota, United States
- CCOP - Missouri Valley Cancer Consortium — Omaha, Nebraska, United States
- Medcenter One Health System — Bismarck, North Dakota, United States
- CCOP - Merit Care Hospital — Fargo, North Dakota, United States
- Altru Health System — Grand Forks, North Dakota, United States
- CCOP - Geisinger Clinic and Medical Center — Danville, Pennsylvania, United States
- Rapid City Regional Hospital — Rapid City, South Dakota, United States
- CCOP - Sioux Community Cancer Consortium — Sioux Falls, South Dakota, United States
Full record on ClinicalTrials.gov
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