Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer in Postmenopausal Women

Completed · Phase 3 · Has a placebo group

Conditions studied: Breast Cancer

In brief

RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using raloxifene and tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. PURPOSE: Randomized double-blinded clinical trial to compare the effectiveness of raloxifene with that of tamoxifen in preventing breast cancer in postmenopausal women.

Key facts

Study ID

NCT00003906

Run by

NSABP Foundation Inc

People needed

19747

Starts

1999-05-01

Expected to finish

2012-08-01

Last updated by the study team

2015-10-06

Who can join

Age: 35 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

• MBCCOP - Gulf Coast — Mobile, Alabama, United States
• Providence Alaska Medical Center — Anchorage, Alaska, United States
• CCOP - Western Regional, Arizona — Phoenix, Arizona, United States
• CCOP - Mayo Clinic Scottsdale Oncology Program — Scottsdale, Arizona, United States
• Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona, United States
• Breast Associates — Fayetteville, Arkansas, United States
• Surgical Associates — Fort Smith, Arkansas, United States
• Northeast Arkansas Clinic — Jonesboro, Arkansas, United States
• Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Kaiser Permanente Medical Center - Anaheim/Orange County — Anaheim, California, United States
• Kaiser Permanente Medical Center - Baldwin Park — Baldwin Park, California, United States
• Kaiser Permanente Medical Center - Bellflower — Bellflower, California, United States
• Alta Bates Comprehensive Cancer Center — Berkeley, California, United States
• Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
• Mills-Peninsula Health Services — Burlingame, California, United States
• Enloe Cancer Center at Enloe Medical Center — Chico, California, United States
• Mount Diablo Medical Center — Concord, California, United States
• Corona Regional Medical Center — Corona, California, United States
• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Scripps Memorial Hospitals-Stevens Cancer Center - Encinitas — Encinitas, California, United States
• North Bay Cancer Center — Fairfield, California, United States
• Kaiser Permanente Medical Center - Fontana — Fontana, California, United States
• Crosson Cancer Center at St. Jude Medical Center — Fullerton, California, United States
• Glendale Memorial Hospital Comprehensive Cancer Center — Glendale, California, United States
• Comprehensive Cancer Institute — Huntsville, Alabama, United States

Full record on ClinicalTrials.gov

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