Trastuzumab Plus Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Completed · Phase 2

Conditions studied: Lung Cancer

In brief

RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining monoclonal antibody therapy with chemotherapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of the monoclonal antibody trastuzumab plus carboplatin and paclitaxel in treating patients who have advanced non-small cell lung cancer.

Key facts

Study ID

NCT00003881

Run by

Eastern Cooperative Oncology Group

Starts

1999-05-01

Expected to finish

2004-07-01

Last updated by the study team

2013-06-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Beckman Research Institute, City of Hope — Los Angeles, California, United States
• Veterans Affairs Medical Center - Palo Alto — Palo Alto, California, United States
• Stanford University Medical Center — Stanford, California, United States
• CCOP - Colorado Cancer Research Program, Inc. — Denver, Colorado, United States
• CCOP - Christiana Care Health Services — Wilmington, Delaware, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• Veterans Affairs Medical Center - Gainsville — Gainesville, Florida, United States
• Sylvester Cancer Center, University of Miami — Miami, Florida, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• Veterans Affairs Medical Center - Tampa (Haley) — Tampa, Florida, United States
• Emory University Hospital - Atlanta — Atlanta, Georgia, United States
• Veterans Affairs Medical Center - Atlanta (Decatur) — Decatur, Georgia, United States
• Robert H. Lurie Comprehensive Cancer Center, Northwestern University — Chicago, Illinois, United States
• Veterans Affairs Medical Center - Chicago (Lakeside) — Chicago, Illinois, United States
• CCOP - Central Illinois — Decatur, Illinois, United States
• CCOP - Evanston — Evanston, Illinois, United States
• CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Veterans Affairs Medical Center - Indianapolis (Roudebush) — Indianapolis, Indiana, United States
• CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
• CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
• CCOP - Wichita — Wichita, Kansas, United States
• MBCCOP - LSU Medical Center — New Orleans, Louisiana, United States
• CCOP - Scottsdale Oncology Program — Scottsdale, Arizona, United States

Full record on ClinicalTrials.gov

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