Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors

Completed · Phase 2

Conditions studied: Childhood Germ Cell Tumor, Drug/Agent Toxicity by Tissue/Organ, Extragonadal Germ Cell Tumor, Ovarian Cancer

In brief

RATIONALE: Chemotherapy drugs use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase I trial to study the effectiveness of high-dose cisplatin, etoposide, and bleomycin plus amifostine in treating children who have malignant germ cell tumors.

Key facts

Study ID
NCT00003811
Run by
Children's Oncology Group
People needed
27
Starts
2000-04-01
Expected to finish
2007-09-01
Last updated by the study team
2013-07-04

Who can join

Age: any, up to 14. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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