Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma

Completed

Conditions studied: Leukemia, Myelodysplastic Syndromes, Sarcoma

In brief

RATIONALE: Determination of genetic markers for soft tissue sarcoma or rhabdomyosarcoma may help doctors identify patients who are at risk for therapy-related leukemia. PURPOSE: Clinical trial to study genetic testing of children with soft tissue sarcoma or rhabdomyosarcoma to identify children who are at risk of developing leukemia from the chemotherapy used to treat sarcoma.

Key facts

Study ID

NCT00003793

Run by

Children's Oncology Group

People needed

294

Starts

1998-12-01

Expected to finish

2007-03-01

Last updated by the study team

2014-08-05

Who can join

Age: any, up to 17. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Jonathan Jaques Children's Cancer Center at Miller Children's Hospital — Long Beach, California, United States
• Jonsson Comprehensive Cancer Center at UCLA — Los Angeles, California, United States
• Children's Hospital Central California — Madera, California, United States
• UCSF Comprehensive Cancer Center — San Francisco, California, United States
• Stanford Comprehensive Cancer Center at Stanford University Medical Center — Stanford, California, United States
• Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center — Farmington, Connecticut, United States
• Alfred I. duPont Hospital for Children — Wilmington, Delaware, United States
• Lombardi Comprehensive Cancer Center at Georgetown University Medical Center — Washington D.C., District of Columbia, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Lee Cancer Care of Lee Memorial Health System — Fort Myers, Florida, United States
• University of Florida Shands Cancer Center — Gainesville, Florida, United States
• Nemours Children's Clinic — Jacksonville, Florida, United States
• Miami Children's Hospital — Miami, Florida, United States
• Baptist-South Miami Regional Cancer Program — Miami, Florida, United States
• Florida Hospital Cancer Institute at Florida Hospital Orlando — Orlando, Florida, United States
• All Children's Hospital — St. Petersburg, Florida, United States
• St. Joseph's Cancer Institute at St. Joseph's Hospital — Tampa, Florida, United States
• Kaplan Cancer Center at St. Mary's Medical Center — West Palm Beach, Florida, United States
• Winship Cancer Institute of Emory University — Atlanta, Georgia, United States
• Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
• Children's Memorial Hospital - Chicago — Chicago, Illinois, United States
• Blank Children's Hospital — Des Moines, Iowa, United States
• Kosair Children's Hospital — Louisville, Kentucky, United States
• Children's Hospital of New Orleans — New Orleans, Louisiana, United States
• Southern California Permanente Medical Group — Downey, California, United States

Full record on ClinicalTrials.gov

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