Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumors
Completed · Phase 1
Conditions studied: Melanoma (Skin), Neuroblastoma, Sarcoma, Unspecified Childhood Solid Tumor, Protocol Specific
In brief
RATIONALE: Biological therapies such as hu14.18-interleukin-2 fusion protein use different ways to stimulate the immune system and stop cancer cells from growing. PURPOSE: Phase I trial to study the effectiveness of hu14.18-interleukin-2 fusion protein in treating children who have refractory or recurrent neuroblastoma or other tumors.
Key facts
- Study ID
- NCT00003750
- Run by
- Children's Oncology Group
- People needed
- 28
- Starts
- 2001-10-01
- Expected to finish
- 2005-09-01
- Last updated by the study team
- 2014-08-08
Who can join
Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Children's Hospital Los Angeles — Los Angeles, California, United States
- Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
- Children's Hospital of Orange County — Orange, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- Stanford Cancer Center at Stanford University Medical Center — Stanford, California, United States
- Children's National Medical Center — Washington D.C., District of Columbia, United States
- Shands Cancer Center at the University of Florida Health Science Center — Gainesville, Florida, United States
- AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish RiteCampus — Atlanta, Georgia, United States
- Children's Memorial Hospital - Chicago — Chicago, Illinois, United States
- Indiana University Cancer Center — Indianapolis, Indiana, United States
- Kansas Cancer Institute at the University of Kansas Medical Center — Kansas City, Kansas, United States
- MBCCOP - LSU Health Sciences Center — New Orleans, Louisiana, United States
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
- Floating Hospital for Children — Boston, Massachusetts, United States
- Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute — Boston, Massachusetts, United States
- University of Michigan Comprehensive Cancer Center — Ann Arbor, Michigan, United States
- Children's Hospital of Michigan — Detroit, Michigan, United States
- University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
- Mayo Clinic Cancer Center — Rochester, Minnesota, United States
- University of Mississippi Medical Center — Jackson, Mississippi, United States
- Children's Mercy Hospital — Kansas City, Missouri, United States
- Arkansas Children's Hospital — Little Rock, Arkansas, United States
Full record on ClinicalTrials.gov
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