Vaccine Therapy Compared With Interferon Alfa in Treating Patients With Stage III Melanoma

Stopped early · Phase 2

Conditions studied: Melanoma (Skin)

In brief

RATIONALE: Vaccines made from a person's melanoma cells may make the body build an immune response to kill tumor cells. Interferon alfa may interfere with the growth of the cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of melanoma vaccine with that of interferon alfa-2b in treating patients who have stage III melanoma that has spread to regional lymph nodes following surgery.

Key facts

Study ID

NCT00003715

Run by

AVAX Technologies

People needed

425

Starts

1998-12-01

Last updated by the study team

2015-12-03

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Cancer and Blood Institute of the Desert — Rancho Mirage, California, United States
• Yale Comprehensive Cancer Center — New Haven, Connecticut, United States
• Columbia - HCA Cancer Research Network — North Miami Beach, Florida, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• Georgia Cancer Specialists — Decatur, Georgia, United States
• University of Illinois at Chicago — Chicago, Illinois, United States
• Lutheran General Cancer Care Center — Park Ridge, Illinois, United States
• James Graham Brown Cancer Center — Louisville, Kentucky, United States
• Cancer and Hematology Centers of Western Michigan — Grand Rapids, Michigan, United States
• Hubert H. Humphrey Cancer Center — Robbinsdale, Minnesota, United States
• Midwest Oncology Consortium — Kansas City, Missouri, United States
• Jersey Shore Cancer Center — Neptune City, New Jersey, United States
• Cancer Institute of New Jersey — New Brunswick, New Jersey, United States
• Herbert Irving Comprehensive Cancer Center — New York, New York, United States
• University of Pennsylvania Cancer Center — Philadelphia, Pennsylvania, United States
• Kimmel Cancer Center of Thomas Jefferson University - Philadelphia — Philadelphia, Pennsylvania, United States
• Palmetto Hematology/Oncology Associates — Spartanburg, South Carolina, United States

Full record on ClinicalTrials.gov

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