Dactinomycin in Treating Patients With Persistent or Recurrent Gestational Trophoblastic Neoplasia

Completed · Phase 2

Conditions studied: Gestational Trophoblastic Tumor

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of dactinomycin in treating patients who have persistent or recurrent gestational trophoblastic neoplasia.

Key facts

Study ID

NCT00003688

Run by

Gynecologic Oncology Group

Starts

1999-10-01

Last updated by the study team

2013-06-10

Who can join

Age: 12 and older, up to 50. Sex: female. Healthy volunteers: not accepted.

Where it is running

• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States
• Community Hospital of Los Gatos — Los Gatos, California, United States
• Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center — Orange, California, United States
• MBCCOP - Hawaii — Honolulu, Hawaii, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
• Albert B. Chandler Medical Center, University of Kentucky — Lexington, Kentucky, United States
• Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support — Bethesda, Maryland, United States
• Tufts - New England Medical Center — Boston, Massachusetts, United States
• University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
• University of Mississippi Medical Center — Jackson, Mississippi, United States
• Cooper University Hospital — Camden, New Jersey, United States
• State University of New York Health Science Center at Brooklyn — Brooklyn, New York, United States
• Long Island Cancer Center at Stony Brook University Hospital — Stony Brook, New York, United States
• Lineberger Comprehensive Cancer Center, UNC — Chapel Hill, North Carolina, United States
• Duke Comprehensive Cancer Center — Durham, North Carolina, United States
• Comprehensive Cancer Center at Wake Forest University — Winston-Salem, North Carolina, United States
• Charles M. Barrett Cancer Center at University Hospital — Cincinnati, Ohio, United States
• Ireland Cancer Center — Cleveland, Ohio, United States
• Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
• Arthur G. James Cancer Hospital - Ohio State University — Columbus, Ohio, United States
• University of Oklahoma College of Medicine — Oklahoma City, Oklahoma, United States
• Abington Memorial Hospital — Abington, Pennsylvania, United States
• Abramson Cancer Center at University of Pennsylvania Medical Center — Philadelphia, Pennsylvania, United States
• Brookview Research, Inc. — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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