Paclitaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer

Completed · Phase 2

Conditions studied: Prostate Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of paclitaxel plus estramustine in treating patients who have metastatic prostate cancer that has not responded to hormone therapy.

Key facts

Study ID

NCT00003614

Run by

Eastern Cooperative Oncology Group

Starts

1999-02-04

Last updated by the study team

2023-06-15

Who can join

Age: 18 and older, up to 120. Sex: male. Healthy volunteers: not accepted.

Where it is running

• Robert H. Lurie Comprehensive Cancer Center, Northwestern University — Chicago, Illinois, United States
• Veterans Affairs Medical Center - Chicago (Lakeside) — Chicago, Illinois, United States
• CCOP - Central Illinois — Decatur, Illinois, United States
• CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• Indiana University Hospitals — Indianapolis, Indiana, United States
• Veterans Affairs Medical Center - Indianapolis (Roudebush) — Indianapolis, Indiana, United States
• CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
• CCOP - Ochsner — New Orleans, Louisiana, United States
• New England Medical Center Hospital — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• CCOP - Kalamazoo — Kalamazoo, Michigan, United States
• CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
• CCOP - Missouri Valley Cancer Consortium — Omaha, Nebraska, United States
• Veterans Affairs Medical Center - East Orange — East Orange, New Jersey, United States
• CCOP - Northern New Jersey — Hackensack, New Jersey, United States
• University of Rochester Cancer Center — Rochester, New York, United States
• CCOP - Merit Care Hospital — Fargo, North Dakota, United States
• Ireland Cancer Center — Cleveland, Ohio, United States
• CCOP - Geisinger Clinical and Medical Center — Danville, Pennsylvania, United States
• University of Pennsylvania Cancer Center — Philadelphia, Pennsylvania, United States
• Fox Chase Cancer Center — Philadelphia, Pennsylvania, United States
• CCOP - MainLine Health — Wynnewood, Pennsylvania, United States
• Veterans Affairs Medical Center - Madison — Madison, Wisconsin, United States
• University of Wisconsin Comprehensive Cancer Center — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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