Combination Chemotherapy and Trastuzumab in Treating Women With Metastatic Breast Cancer
Completed · Phase 2
Conditions studied: Breast Cancer
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: Phase II trial to study the effectiveness of combining paclitaxel, carboplatin, and trastuzumab in treating women who have metastatic breast cancer that overexpresses HER2.
Key facts
- Study ID
- NCT00003612
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 92
- Starts
- 1999-04-01
- Expected to finish
- 2019-03-15
- Last updated by the study team
- 2019-10-08
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
Where it is running
- CCOP - Scottsdale Oncology Program — Scottsdale, Arizona, United States
- Mayo Clinic — Jacksonville, Florida, United States
- CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
- Carle Cancer Center — Urbana, Illinois, United States
- CCOP - Carle Cancer Center — Urbana, Illinois, United States
- CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
- CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
- Siouxland Hematology-Oncology — Sioux City, Iowa, United States
- CCOP - Wichita — Wichita, Kansas, United States
- CCOP - Ochsner — New Orleans, Louisiana, United States
- CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
- CCOP - Duluth — Duluth, Minnesota, United States
- Mayo Clinic Cancer Center — Rochester, Minnesota, United States
- CentraCare Health Plaza — Saint Cloud, Minnesota, United States
- CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
- CCOP - Missouri Valley Cancer Consortium — Omaha, Nebraska, United States
- Medcenter One Health System — Bismarck, North Dakota, United States
- CCOP - Merit Care Hospital — Fargo, North Dakota, United States
- Altru Cancer Center — Grand Forks, North Dakota, United States
- CCOP - Toledo Community Hospital — Toledo, Ohio, United States
- CCOP - Geisinger Clinic and Medical Center — Danville, Pennsylvania, United States
- Rapid City Regional Hospital — Rapid City, South Dakota, United States
- CCOP - Sioux Community Cancer Consortium — Sioux Falls, South Dakota, United States
- CCOP - St. Vincent Hospital Cancer Center, Green Bay — Green Bay, Wisconsin, United States
- Allan Blair Cancer Centre — Regina, Saskatchewan, Canada
Full record on ClinicalTrials.gov
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