Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Completed · Phase 3

Conditions studied: Colorectal Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is most effective in treating advanced colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of various combination chemotherapy regimens in treating patients who have advanced, recurrent, or metastatic colorectal cancer that cannot be treated with surgery or radiation therapy.

Key facts

Study ID

NCT00003594

Run by

Alliance for Clinical Trials in Oncology

People needed

1691

Starts

1998-10-01

Expected to finish

2004-10-01

Last updated by the study team

2020-04-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• MBCCOP - Gulf Coast — Mobile, Alabama, United States
• CCOP - Greater Phoenix — Phoenix, Arizona, United States
• Veterans Affairs Medical Center - Phoenix (Hayden) — Phoenix, Arizona, United States
• Mayo Clinic Hospital — Phoenix, Arizona, United States
• Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
• Veterans Affairs Medical Center - Tucson — Tucson, Arizona, United States
• Arizona Cancer Center — Tucson, Arizona, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Veterans Affairs Medical Center - Little Rock (McClellan) — Little Rock, Arkansas, United States
• Cancer Center and Beckman Research Institute, City of Hope — Duarte, California, United States
• University of California San Diego Cancer Center — La Jolla, California, United States
• Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
• USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
• Veterans Affairs Medical Center - West Los Angeles — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Veterans Affairs Outpatient Clinic - Martinez — Martinez, California, United States
• Community Hospital of the Monterey Peninsula — Monterey, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Chao Family Comprehensive Cancer Center — Orange, California, United States
• Veterans Affairs Medical Center - Palo Alto — Palo Alto, California, United States
• University of California Davis Medical Center — Sacramento, California, United States
• Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
• Veterans Affairs Medical Center - Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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