Interferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin
Completed · Phase 3
Conditions studied: Melanoma (Skin)
In brief
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Interferon alfa-2b may interfere with the growth of cancer cells. It is not yet known whether giving radiation therapy with interferon alfa-2b is more effective than giving interferon alfa-2b alone in treating melanoma. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus interferon alfa-2b with that of interferon alfa-2b alone in treating patients who have melanoma that has metastasized to lymph nodes in the neck, under the arm, or in the groin.
Key facts
- Study ID
- NCT00003444
- Run by
- Eastern Cooperative Oncology Group
- People needed
- 167
- Starts
- 1999-03-29
- Last updated by the study team
- 2023-06-22
Who can join
Age: 18 and older, up to 120. Sex: female. Healthy volunteers: not accepted.
Where it is running
- Emory University Hospital - Atlanta — Atlanta, Georgia, United States
- Veterans Affairs Medical Center - Atlanta (Decatur) — Decatur, Georgia, United States
- Robert H. Lurie Comprehensive Cancer Center, Northwestern University — Chicago, Illinois, United States
- Veterans Affairs Medical Center - Chicago (Lakeside) — Chicago, Illinois, United States
- CCOP - Central Illinois — Decatur, Illinois, United States
- CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
- CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
- New England Medical Center Hospital — Boston, Massachusetts, United States
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
- CCOP - Kalamazoo — Kalamazoo, Michigan, United States
- CCOP - Duluth — Duluth, Minnesota, United States
- CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
- Veterans Affairs Medical Center - East Orange — East Orange, New Jersey, United States
- CCOP - Northern New Jersey — Hackensack, New Jersey, United States
- Hackensack University Medical Center — Hackensack, New Jersey, United States
- Riverview Medical Center — Red Bank, New Jersey, United States
- Veterans Affairs Medical Center - Albany — Albany, New York, United States
- Ireland Cancer Center — Cleveland, Ohio, United States
- CCOP - Geisinger Clinical and Medical Center — Danville, Pennsylvania, United States
- University of Pittsburgh Cancer Institute — Pittsburgh, Pennsylvania, United States
- UPMC St. Margaret — Pittsburgh, Pennsylvania, United States
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States
- Veterans Affairs Medical Center - Milwaukee (Zablocki) — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
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