Amifostine Plus Topotecan in Treating Patients With Myelodysplastic Syndrome

Completed · Phase 1/Phase 2

Conditions studied: Leukemia, Myelodysplastic Syndromes

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase I/II trial to study the effectiveness of amifostine plus topotecan in treating patients with myelodysplastic syndrome.

Key facts

Study ID

NCT00003415

Run by

University of Arizona

People needed

26

Starts

1998-09-01

Expected to finish

2002-11-01

Last updated by the study team

2013-01-31

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Arizona Cancer Center — Tucson, Arizona, United States

Full record on ClinicalTrials.gov

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