Carboplatin, Paclitaxel, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed During Surgery
Completed · Phase 3
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether giving chemotherapy before combined chemotherapy and radiation therapy is more effective than combined chemotherapy and radiation therapy alone in treating patients with non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of carboplatin and paclitaxel followed by radiation therapy and chemotherapy with radiation therapy and chemotherapy alone in treating patients with stage III non-small cell lung cancer that cannot be removed during surgery.
Key facts
- Study ID
- NCT00003387
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 366
- Starts
- 1998-07-01
- Expected to finish
- 2009-04-01
- Last updated by the study team
- 2016-07-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Veterans Affairs Medical Center - Birmingham — Birmingham, Alabama, United States
- University of California San Diego Cancer Center — La Jolla, California, United States
- Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
- UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
- CCOP - Christiana Care Health Services — Wilmington, Delaware, United States
- Howard University Cancer Center — Washington D.C., District of Columbia, United States
- Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
- CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
- University of Illinois at Chicago Health Sciences Center — Chicago, Illinois, United States
- Veterans Affairs Medical Center - Chicago (Westside Hospital) — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Hematology Oncology Associates of the Quad Cities — Bettendorf, Iowa, United States
- Holden Comprehensive Cancer Center at The University of Iowa — Iowa City, Iowa, United States
- Veterans Affairs Medical Center - Togus — Togus, Maine, United States
- Marlene & Stewart Greenebaum Cancer Center, University of Maryland — Baltimore, Maryland, United States
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States
- University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
- Veterans Affairs Medical Center - Minneapolis — Minneapolis, Minnesota, United States
- Veterans Affairs Medical Center - Columbia (Truman Memorial) — Columbia, Missouri, United States
- Ellis Fischel Cancer Center - Columbia — Columbia, Missouri, United States
- Barnes-Jewish Hospital — St Louis, Missouri, United States
- University of Nebraska Medical Center — Omaha, Nebraska, United States
- CCOP - Southern Nevada Cancer Research Foundation — Las Vegas, Nevada, United States
- Norris Cotton Cancer Center — Lebanon, New Hampshire, United States
- Cooper Cancer Institute — Camden, New Jersey, United States
Full record on ClinicalTrials.gov
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