Radiation Therapy Plus Paclitaxel and Cisplatin in Treating Patients With Cervical Cancer
Completed · Phase 1/Phase 2
Conditions studied: Cervical Cancer
In brief
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Paclitaxel and cisplatin may increase the effectiveness of radiation therapy by making the tumor cells more sensitive to radiation. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy to the pelvis plus paclitaxel and cisplatin in treating patients who have cervical cancer.
Key facts
- Study ID
- NCT00003379
- Run by
- Gynecologic Oncology Group
- People needed
- 40
- Starts
- 1999-11-01
- Last updated by the study team
- 2013-05-27
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
Where it is running
- CCOP - Western Regional, Arizona — Phoenix, Arizona, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- MBCCOP - University of Illinois at Chicago — Chicago, Illinois, United States
- CCOP - Central Illinois — Decatur, Illinois, United States
- CCOP - Evanston — Evanston, Illinois, United States
- CCOP - Carle Cancer Center — Urbana, Illinois, United States
- Indiana University Cancer Center — Indianapolis, Indiana, United States
- Saint Joseph Regional Medical Center — South Bend, Indiana, United States
- Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
- Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support — Bethesda, Maryland, United States
- CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
- CCOP - Grand Rapids — Grand Rapids, Michigan, United States
- CCOP - Kalamazoo — Kalamazoo, Michigan, United States
- CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
- University of Mississippi Medical Center — Jackson, Mississippi, United States
- CCOP - Kansas City — Kansas City, Missouri, United States
- CCOP - Cancer Research for the Ozarks — Springfield, Missouri, United States
- CCOP - Missouri Valley Cancer Consortium — Omaha, Nebraska, United States
- Cooper University Hospital — Camden, New Jersey, United States
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina, United States
- Comprehensive Cancer Center at Wake Forest University — Winston-Salem, North Carolina, United States
- Ireland Cancer Center — Cleveland, Ohio, United States
- Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
- University of Oklahoma College of Medicine — Oklahoma City, Oklahoma, United States
- CCOP - Columbia River Oncology Program — Portland, Oregon, United States
Full record on ClinicalTrials.gov
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