Irinotecan in Treating Patients With Solid Tumors or Lymphoma Who Have Abnormal Liver or Kidney Function or Who Have Received Radiation Therapy to the Pelvis

Completed · Phase 1

Conditions studied: Lymphoma, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Irinotecan may be effective in treating patients with abnormal liver or kidney function or who have received radiation therapy. PURPOSE: Phase I trial to study the effectiveness of irinotecan in treating patients with solid tumors or lymphoma who have abnormal liver or kidney function or who have had previous radiation therapy to the pelvis.

Key facts

Study ID

NCT00003368

Run by

National Cancer Institute (NCI)

Starts

1998-06-01

Expected to finish

2006-07-01

Last updated by the study team

2013-03-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Veterans Affairs Medical Center - Birmingham — Birmingham, Alabama, United States
• University of California San Diego Cancer Center — La Jolla, California, United States
• Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• CCOP - Christiana Care Health Services — Wilmington, Delaware, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
• University of Illinois at Chicago Health Sciences Center — Chicago, Illinois, United States
• Veterans Affairs Medical Center - Chicago (Westside Hospital) — Chicago, Illinois, United States
• University of Chicago Cancer Research Center — Chicago, Illinois, United States
• Holden Comprehensive Cancer Center at The University of Iowa — Iowa City, Iowa, United States
• Veterans Affairs Medical Center - Togus — Togus, Maine, United States
• Marlene & Stewart Greenebaum Cancer Center, University of Maryland — Baltimore, Maryland, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
• Veterans Affairs Medical Center - Minneapolis — Minneapolis, Minnesota, United States
• Veterans Affairs Medical Center - Columbia (Truman Memorial) — Columbia, Missouri, United States
• Ellis Fischel Cancer Center - Columbia — Columbia, Missouri, United States
• Barnes-Jewish Hospital — St Louis, Missouri, United States
• University of Nebraska Medical Center — Omaha, Nebraska, United States
• CCOP - Southern Nevada Cancer Research Foundation — Las Vegas, Nevada, United States
• Norris Cotton Cancer Center — Lebanon, New Hampshire, United States
• Veterans Affairs Medical Center - Buffalo — Buffalo, New York, United States
• Roswell Park Cancer Institute — Buffalo, New York, United States
• CCOP - North Shore University Hospital — Manhasset, New York, United States

Full record on ClinicalTrials.gov

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