High-Dose Melphalan Plus Peripheral Stem Cell Transplantation in Treating Patients With Primary Systemic Amyloidosis

Completed · Phase 2

Conditions studied: Multiple Myeloma and Plasma Cell Neoplasm

In brief

RATIONALE: High-dose chemotherapy may destroy the amyloid-producing cells in bone marrow. Peripheral stem cell transplantation PURPOSE: Phase II trial to study the effectiveness of high dose melphalan plus peripheral stem cell transplantation in treating patients who have primary systemic amyloidosis.

Key facts

Study ID

NCT00003353

Run by

Eastern Cooperative Oncology Group

Starts

1998-11-16

Last updated by the study team

2023-06-22

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

Where it is running

• CCOP - Scottsdale Oncology Program — Scottsdale, Arizona, United States
• Sylvester Cancer Center, University of Miami — Miami, Florida, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• CCOP - Evanston — Evanston, Illinois, United States
• CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Veterans Affairs Medical Center - Indianapolis (Roudebush) — Indianapolis, Indiana, United States
• New England Medical Center Hospital — Boston, Massachusetts, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
• University of Rochester Cancer Center — Rochester, New York, United States
• Ireland Cancer Center — Cleveland, Ohio, United States
• Veterans Affairs Medical Center - Nashville — Nashville, Tennessee, United States
• Vanderbilt Cancer Center — Nashville, Tennessee, United States
• CCOP - Marshfield Medical Research and Education Foundation — Marshfield, Wisconsin, United States
• Medical College of Wisconsin — Milwaukee, Wisconsin, United States
• Veterans Affairs Medical Center - Milwaukee (Zablocki) — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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