Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer
Completed · Phase 3
Conditions studied: Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Oral Complications, Radiation Toxicity
In brief
RATIONALE: Amifostine may be an effective treatment for the toxic side effects caused by radiation therapy and chemotherapy. It is not yet known whether chemotherapy and radiation therapy are more effective with or without amifostine for non-small cell lung cancer. PURPOSE: Randomized phase III trial to determine the effectiveness of amifostine in treating patients who have stage II or stage III non-small cell lung cancer that cannot be surgically removed and who are undergoing chemotherapy and radiation therapy.
Key facts
- Study ID
- NCT00003313
- Run by
- Radiation Therapy Oncology Group
- People needed
- 243
- Starts
- 1998-09-01
- Expected to finish
- 2010-06-01
- Last updated by the study team
- 2014-11-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Huntsville Hospital System — Huntsville, Alabama, United States
- Comprehensive Cancer Institute of Huntsville — Huntsville, Alabama, United States
- MBCCOP - Gulf Coast — Mobile, Alabama, United States
- Alabama Oncology, LLC — Montgomery, Alabama, United States
- Radiation Oncology Associates of West Alabama — Tuscallosa, Alabama, United States
- Providence Alaska Medical Center — Anchorage, Alaska, United States
- Foundation for Cancer Research and Education — Phoenix, Arizona, United States
- Arizona Cancer Center — Tucson, Arizona, United States
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Mount Diablo Medical Center — Concord, California, United States
- Cancer Center and Beckman Research Institute, City of Hope — Duarte, California, United States
- California Cancer Center — Fresno, California, United States
- Saint Agnes Cancer Center — Fresno, California, United States
- Glendale Memorial Hospital and Health Center — Glendale, California, United States
- Sutter Health West Cancer Research Group — Greenbrae, California, United States
- University of California San Diego Cancer Center — La Jolla, California, United States
- Loma Linda University Medical Center — Loma Linda, California, United States
- Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Huntington Cancer Center — Pasadena, California, United States
- Cancer Care Center — Pomona, California, United States
- Radiation Oncology Center - Sacramento — Sacramento, California, United States
- University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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