Fluorouracil, Gemcitabine, and Radiation Therapy in Treating Patients With Cancer of the Pancreas

Completed · Phase 3

Conditions studied: Pancreatic Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining radiation therapy with chemotherapy may kill more tumor cells. It is not yet known which treatment regimen is most effective for pancreatic cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of fluorouracil and gemcitabine plus radiation therapy in treating patients with cancer of the pancreas who have undergone surgery.

Key facts

Study ID

NCT00003216

Run by

Radiation Therapy Oncology Group

People needed

518

Starts

1998-07-01

Last updated by the study team

2013-11-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• MBCCOP - Gulf Coast — Mobile, Alabama, United States
• CCOP - Greater Phoenix — Phoenix, Arizona, United States
• Veterans Affairs Medical Center - Phoenix (Carl T. Hayden) — Phoenix, Arizona, United States
• Veterans Affairs Medical Center - Tucson — Tucson, Arizona, United States
• Arizona Cancer Center — Tucson, Arizona, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Veterans Affairs Medical Center - Little Rock (McClellan) — Little Rock, Arkansas, United States
• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
• Veterans Affairs Medical Center - West Los Angeles — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Veterans Affairs Outpatient Clinic - Martinez — Martinez, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Chao Family Comprehensive Cancer Center — Orange, California, United States
• University of California Davis Medical Center — Sacramento, California, United States
• Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
• CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
• David Grant Medical Center — Travis Air Force Base, California, United States
• University of Colorado Cancer Center — Denver, Colorado, United States
• Veterans Affairs Medical Center - Denver — Denver, Colorado, United States
• MBCCOP - Howard University Cancer Center — Washington D.C., District of Columbia, United States
• Mayo Clinic — Jacksonville, Florida, United States
• CCOP - Atlanta Regional — Atlanta, Georgia, United States
• Dwight David Eisenhower Army Medical Center — Fort Gordon, Georgia, United States
• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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