Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor
Completed · Phase 2
Conditions studied: Brain and Central Nervous System Tumors
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy and radiation therapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy or radiation therapy and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with topotecan, cyclophosphamide, cisplatin, and vincristine plus radiation therapy and peripheral stem cell transplantation in treating children with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor.
Key facts
- Study ID
- NCT00003211
- Run by
- St. Jude Children's Research Hospital
- People needed
- 94
- Starts
- 1996-10-01
- Expected to finish
- 2007-06-01
- Last updated by the study team
- 2012-11-07
Who can join
Age: 3 and older, up to 20. Sex: any. Healthy volunteers: not accepted.
Where it is running
- St. Jude Children's Research Hospital — Memphis, Tennessee, United States
- Texas Children's Cancer Center — Houston, Texas, United States
- Children's Hospital at Westmead — Westmead, New South Wales, Australia
- Royal Children's Hospital — Parkville, Victoria, Australia
Full record on ClinicalTrials.gov
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