Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma
Completed · Phase 2/Phase 3
Conditions studied: Leukemia, Lymphoma, Myelodysplastic Syndromes
In brief
RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill cancer cells. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Eliminating the T cells from the donor cells before transplanting them may prevent this from happening. PURPOSE: Randomized phase II/III trial to compare the effectiveness of conventional bone marrow transplantation with T cell-depleted bone marrow transplantation in treating patients who have leukemia, myelodysplasia, or lymphoblastic lymphoma.
Key facts
- Study ID
- NCT00003187
- Run by
- Virginia Commonwealth University
- People needed
- 19
- Starts
- 1995-05-01
- Expected to finish
- 2005-02-01
- Last updated by the study team
- 2010-02-24
Who can join
Age: any, up to 55. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Stanford University Medical Center — Stanford, California, United States
- University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
- Albert B. Chandler Medical Center, University of Kentucky — Lexington, Kentucky, United States
- University of Minnesota Medical School — Minneapolis, Minnesota, United States
- Memorial Sloan-Kettering Cancer Center — New York, New York, United States
- Duke Comprehensive Cancer Center — Durham, North Carolina, United States
- Comprehensive Cancer Center of Wake Forest University Baptist Medical Center — Winston-Salem, North Carolina, United States
- Arthur G. James Cancer Hospital - Ohio State University — Columbus, Ohio, United States
- Western Pennsylvania Hospital — Pittsburgh, Pennsylvania, United States
- University of South Carolina School of Medicine — Columbia, South Carolina, United States
- Huntsman Cancer Institute — Salt Lake City, Utah, United States
- Massey Cancer Center — Richmond, Virginia, United States
- Midwest Children's Cancer Center — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
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