Surgery With or Without Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus
Completed · Phase 3
Conditions studied: Esophageal Cancer
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether surgery is more effective with or without chemotherapy and radiation therapy for cancer of the esophagus. PURPOSE: Randomized phase III trial to compare the effectiveness of surgery with or without combination chemotherapy and radiation therapy in treating patients who have cancer of the esophagus that can be surgically removed.
Key facts
- Study ID
- NCT00003118
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 56
- Starts
- 1997-10-01
- Expected to finish
- 2000-03-01
- Last updated by the study team
- 2016-07-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of California San Diego Cancer Center — La Jolla, California, United States
- UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
- CCOP - Christiana Care Health Services — Wilmington, Delaware, United States
- Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
- CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
- University of Illinois at Chicago Health Sciences Center — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
- Marlene & Stewart Greenebaum Cancer Center, University of Maryland — Baltimore, Maryland, United States
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States
- University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
- University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
- Ellis Fischel Cancer Center - Columbia — Columbia, Missouri, United States
- Barnes-Jewish Hospital — St Louis, Missouri, United States
- University of Nebraska Medical Center — Omaha, Nebraska, United States
- CCOP - Southern Nevada Cancer Research Foundation — Las Vegas, Nevada, United States
- Norris Cotton Cancer Center — Lebanon, New Hampshire, United States
- Fox Chase Cancer Center at Virtua-Memorial Hospital Burlington County — Mount Holly, New Jersey, United States
- St. Joseph's Hospital and Medical Center — Paterson, New Jersey, United States
- Roswell Park Cancer Institute — Buffalo, New York, United States
- CCOP - North Shore University Hospital — Manhasset, New York, United States
- North Shore University Hospital — Manhasset, New York, United States
- Memorial Sloan-Kettering Cancer Center — New York, New York, United States
- New York Presbyterian Hospital - Cornell Campus — New York, New York, United States
- Mount Sinai Medical Center, NY — New York, New York, United States
Full record on ClinicalTrials.gov
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