Marimastat or No Further Therapy in Treating Women With Metastatic Breast Cancer That Is Responding or Stable Following Chemotherapy

Completed · Phase 3

Conditions studied: Breast Cancer

In brief

RATIONALE: Marimastat may stop the growth of breast cancer by stopping blood flow to the tumor. It is not known whether chemotherapy is more effective with or without marimastat for breast cancer. PURPOSE: Randomized double-blinded phase III trial to compare the effectiveness of marimastat with that of no further therapy in treating women who have metastatic breast cancer that is responding or stable after chemotherapy.

Key facts

Study ID

NCT00003010

Run by

Eastern Cooperative Oncology Group

People needed

334

Starts

1997-12-02

Last updated by the study team

2023-06-15

Who can join

Age: 18 and older, up to 120. Sex: female. Healthy volunteers: not accepted.

Where it is running

• CCOP - Scottsdale Oncology Program — Scottsdale, Arizona, United States
• Robert H. Lurie Comprehensive Cancer Center, Northwestern University — Chicago, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
• CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
• Siouxland Hematology-Oncology — Sioux City, Iowa, United States
• CCOP - Wichita — Wichita, Kansas, United States
• CCOP - Duluth — Duluth, Minnesota, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• CentraCare Clinic — Saint Cloud, Minnesota, United States
• CCOP - Missouri Valley Cancer Consortium — Omaha, Nebraska, United States
• Trinitas Hospital - Jersey Street Campus — Elizabeth, New Jersey, United States
• Hunterdon Regional Cancer Center — Flemington, New Jersey, United States
• Hackensack University Medical Center — Hackensack, New Jersey, United States
• Morristown Memorial Hospital — Morristown, New Jersey, United States
• Riverview Medical Center — Red Bank, New Jersey, United States
• St. Francis Medical Center — Trenton, New Jersey, United States
• Albert Einstein Comprehensive Cancer Center — The Bronx, New York, United States
• Medcenter One Health System — Bismarck, North Dakota, United States
• Altru Health Systems — Grand Forks, North Dakota, United States
• CCOP - Columbus — Columbus, Ohio, United States
• CCOP - Toledo Community Hospital Oncology Program — Toledo, Ohio, United States
• Hahnemann University Hospital — Philadelphia, Pennsylvania, United States
• Rapid City Regional Hospital — Rapid City, South Dakota, United States
• CCOP - Sioux Community Cancer Consortium — Sioux Falls, South Dakota, United States

Full record on ClinicalTrials.gov

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