Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Completed · Phase 3

Conditions studied: Sarcoma

In brief

RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether chemotherapy is more effective with or without radiation therapy in treating patients who have rhabdomyosarcoma. PURPOSE: Phase III trial to compare the effectiveness of chemotherapy with or without radiation therapy in treating patients who have newly-diagnosed rhabdomyosarcoma.

Key facts

Study ID

NCT00002995

Run by

Children's Oncology Group

People needed

483

Starts

1997-08-01

Expected to finish

2011-01-01

Last updated by the study team

2014-02-14

Who can join

Age: any, up to 49. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of South Alabama Cancer Research Institute — Mobile, Alabama, United States
• Phoenix Children's Hospital — Phoenix, Arizona, United States
• Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona, United States
• Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Southern California Permanente Medical Group — Downey, California, United States
• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
• Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda, California, United States
• Jonathan Jaques Children's Cancer Center at Miller Children's Hospital — Long Beach, California, United States
• Children's Hospital Los Angeles — Los Angeles, California, United States
• Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Children's Hospital Central California — Madera, California, United States
• Children's Hospital and Research Center at Oakland — Oakland, California, United States
• Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center — Orange, California, United States
• Children's Hospital of Orange County — Orange, California, United States
• Lucile Packard Children's Hospital at Stanford University Medical Center — Palo Alto, California, United States
• Sutter Cancer Center — Sacramento, California, United States
• University of California Davis Cancer Center — Sacramento, California, United States
• Kaiser Permanente Medical Center - Sacramento — Sacramento, California, United States
• Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego — San Diego, California, United States
• Children's Hospital and Health Center, San Diego — San Diego, California, United States
• UCSF Comprehensive Cancer Center — San Francisco, California, United States
• Santa Barbara Cottage Hospital — Santa Barbara, California, United States
• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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