Gene Mutations in Patients With Advanced Prostate Cancer That Is Not Responsive to Hormone Therapy

Completed

Conditions studied: Prostate Cancer

In brief

RATIONALE: Gene mutations may make prostate cancer cells unable to attach to androgens. This may permit the growth of prostate cancer. Gene testing may improve the identification of patients with advanced prostate cancer. PURPOSE: Clinical trial to study the androgen receptor gene in patients with prostate cancer that is not responsive to hormone therapy.

Key facts

Study ID

NCT00002924

Run by

Alliance for Clinical Trials in Oncology

People needed

184

Starts

1997-01-01

Expected to finish

2006-06-01

Last updated by the study team

2016-07-14

Who can join

Age: any. Sex: male. Healthy volunteers: not accepted.

Where it is running

• Veterans Affairs Medical Center - Birmingham — Birmingham, Alabama, United States
• University of California San Diego Cancer Center — La Jolla, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
• CCOP - Christiana Care Health Services — Wilmington, Delaware, United States
• Vincent T. Lombardi Cancer Research Center, Georgetown University — Washington D.C., District of Columbia, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
• University of Illinois at Chicago Health Sciences Center — Chicago, Illinois, United States
• Veterans Affairs Medical Center - Chicago (Westside Hospital) — Chicago, Illinois, United States
• University of Chicago Cancer Research Center — Chicago, Illinois, United States
• University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
• Veterans Affairs Medical Center - Togus — Togus, Maine, United States
• Marlene & Stewart Greenebaum Cancer Center, University of Maryland — Baltimore, Maryland, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
• Veterans Affairs Medical Center - Minneapolis — Minneapolis, Minnesota, United States
• University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
• Veterans Affairs Medical Center - Columbia (Truman Memorial) — Columbia, Missouri, United States
• Ellis Fischel Cancer Center - Columbia — Columbia, Missouri, United States
• Barnes-Jewish Hospital — St Louis, Missouri, United States
• University of Nebraska Medical Center — Omaha, Nebraska, United States
• CCOP - Southern Nevada Cancer Research Foundation — Las Vegas, Nevada, United States
• Norris Cotton Cancer Center — Lebanon, New Hampshire, United States
• St. Barnabas Medical Center — Livingston, New Jersey, United States

Full record on ClinicalTrials.gov

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