Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

Completed · Phase 3

Conditions studied: Head and Neck Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether cisplatin plus fluorouracil are more effective than paclitaxel plus cisplatin in treating patients with advanced head and neck cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens in treating patients with advanced head and neck cancer.

Key facts

Study ID

NCT00002888

Run by

Eastern Cooperative Oncology Group

Starts

1997-03-01

Expected to finish

2004-08-01

Last updated by the study team

2013-06-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• CCOP - Greater Phoenix — Phoenix, Arizona, United States
• Veterans Affairs Medical Center - Phoenix (Hayden) — Phoenix, Arizona, United States
• Veterans Affairs Medical Center - Tucson — Tucson, Arizona, United States
• Arizona Cancer Center — Tucson, Arizona, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Veterans Affairs Medical Center - Little Rock (McClellan) — Little Rock, Arkansas, United States
• Beckman Research Institute, City of Hope — Duarte, California, United States
• Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
• USC/Norris Comprehensive Cancer Center — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Veterans Affairs Outpatient Clinic - Martinez — Martinez, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Chao Family Comprehensive Cancer Center — Orange, California, United States
• University of California Davis Medical Center — Sacramento, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
• David Grant Medical Center — Travis Air Force Base, California, United States
• Veterans Affairs Medical Center - Denver — Denver, Colorado, United States
• University of Colorado Cancer Center — Denver, Colorado, United States
• CCOP - Atlanta Regional — Atlanta, Georgia, United States
• Dwight David Eisenhower Army Medical Center — Fort Gordon, Georgia, United States
• Cancer Research Center of Hawaii — Honolulu, Hawaii, United States
• Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital) — Hines, Illinois, United States
• Loyola University Medical Center — Maywood, Illinois, United States
• MBCCOP - University of South Alabama — Mobile, Alabama, United States

Full record on ClinicalTrials.gov

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