Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia

Completed · Phase 3

Conditions studied: Leukemia

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug and giving the drugs in different combinations may kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of standard combination chemotherapy treatment with more intensive combination chemotherapy in treating children with acute lymphocytic leukemia.

Key facts

Study ID

NCT00002812

Run by

Children's Oncology Group

People needed

2078

Starts

1996-09-01

Last updated by the study team

2013-08-26

Who can join

Age: 1 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Long Beach Memorial Medical Center — Long Beach, California, United States
• Children's Hospital Los Angeles — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Children's Hospital of Orange County — Orange, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• Children's Hospital of Denver — Denver, Colorado, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• University of Chicago Cancer Research Center — Chicago, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Holden Comprehensive Cancer Center at The University of Iowa — Iowa City, Iowa, United States
• University of Michigan Comprehensive Cancer Center — Ann Arbor, Michigan, United States
• University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• Children's Mercy Hospital — Kansas City, Missouri, United States
• University of Nebraska Medical Center — Omaha, Nebraska, United States
• Saint Peter's University Hospital — New Brunswick, New Jersey, United States
• NYU School of Medicine's Kaplan Comprehensive Cancer Center — New York, New York, United States
• Memorial Sloan-Kettering Cancer Center — New York, New York, United States
• Mount Sinai School of Medicine — New York, New York, United States
• Herbert Irving Comprehensive Cancer Center — New York, New York, United States
• Lineberger Comprehensive Cancer Center, UNC — Chapel Hill, North Carolina, United States
• Children's Hospital Medical Center - Cincinnati — Cincinnati, Ohio, United States
• Ireland Cancer Center — Cleveland, Ohio, United States
• Children's Hospital of Columbus — Columbus, Ohio, United States
• Doernbecher Children's Hospital — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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