Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer
Completed · Phase 3
Conditions studied: Colorectal Cancer, Metastatic Cancer
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which chemotherapy regimen is more effective for metastatic colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of intrahepatic floxuridine, leucovorin, and dexamethasone with that of systemic fluorouracil and leucovorin in treating patients who have unresectable liver metastases from colorectal cancer.
Key facts
- Study ID
- NCT00002716
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 135
- Starts
- 1996-01-01
- Expected to finish
- 2006-08-01
- Last updated by the study team
- 2016-07-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
- CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
- John Stoddard Cancer Center at Iowa Methodist Medical Center — Des Moines, Iowa, United States
- Mercy Cancer Center at Mercy Medical Center-Des Moines — Des Moines, Iowa, United States
- Iowa Lutheran Hospital — Des Moines, Iowa, United States
- Midlands Cancer Center at Midlands Community Hospital — Papillion, Nebraska, United States
- MBCCOP - University of New Mexico HSC — Albuquerque, New Mexico, United States
- MetroHealth Medical Center — Cleveland, Ohio, United States
- Penn State Cancer Institute at Milton S. Hershey Medical Center — Hershey, Pennsylvania, United States
- Fox Chase Cancer Center — Philadelphia, Pennsylvania, United States
- CCOP - St. Vincent Hospital Cancer Center, Green Bay — Green Bay, Wisconsin, United States
- Westmead Hospital — Westmead, New South Wales, Australia
- Instituto de Enfermedades Neoplasicas — Lima, Peru
- San Juan City Hospital — San Juan, Puerto Rico
Full record on ClinicalTrials.gov
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