Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia

Completed · Phase 2

Conditions studied: Leukemia

In brief

Phase II trial to study the effectiveness of radiation therapy following chemotherapy in treating children with CNS relapse from acute lymphoblastic leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with radiation therapy may kill more cancer cells.

Key facts

Study ID

NCT00002704

Run by

National Cancer Institute (NCI)

People needed

156

Starts

1996-01-01

Last updated by the study team

2013-02-01

Who can join

Age: any, up to 20. Sex: any. Healthy volunteers: not accepted.

Where it is running

• MBCCOP - University of South Alabama — Mobile, Alabama, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• University of California San Diego Cancer Center — La Jolla, California, United States
• Lucile Packard Children's Hospital at Stanford — Palo Alto, California, United States
• University of California Davis Medical Center — Sacramento, California, United States
• Children's Hospital and Health Center — San Diego, California, United States
• Yale Comprehensive Cancer Center — New Haven, Connecticut, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• Shands Hospital and Clinics, University of Florida — Gainesville, Florida, United States
• Sylvester Cancer Center, University of Miami — Miami, Florida, United States
• Miami Children's Hospital — Miami, Florida, United States
• CCOP - Florida Pediatric — Tampa, Florida, United States
• Emory University Hospital - Atlanta — Atlanta, Georgia, United States
• Children's Memorial Hospital, Chicago — Chicago, Illinois, United States
• University of Kansas Medical Center — Kansas City, Kansas, United States
• CCOP - Wichita — Wichita, Kansas, United States
• Via Christi Regional Medical Center — Wichita, Kansas, United States
• MBCCOP - LSU Medical Center — New Orleans, Louisiana, United States
• Tulane University School of Medicine — New Orleans, Louisiana, United States
• CCOP - Ochsner — New Orleans, Louisiana, United States
• Marlene & Stewart Greenebaum Cancer Center, University of Maryland — Baltimore, Maryland, United States
• Johns Hopkins Oncology Center — Baltimore, Maryland, United States
• Boston Floating Hospital Infants and Children — Boston, Massachusetts, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• University of Alabama Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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