Radiation Therapy With or Without Chemotherapy in Treating Patients With Head and Neck Cancer That Has Been Removed During Surgery
Completed · Phase 3
Conditions studied: Head and Neck Cancer
In brief
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether radiation therapy plus cisplatin is more effective than radiation therapy alone in treating patients with head and neck cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus cisplatin with radiation therapy alone in treating patients with head and neck cancer that has been removed during surgery.
Key facts
- Study ID
- NCT00002670
- Run by
- Radiation Therapy Oncology Group
- People needed
- 459
- Starts
- 1995-09-01
- Expected to finish
- 2013-11-01
- Last updated by the study team
- 2014-01-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
- Emory University Hospital - Atlanta — Atlanta, Georgia, United States
- Veterans Affairs Medical Center - Atlanta (Decatur) — Decatur, Georgia, United States
- CCOP - Evanston — Evanston, Illinois, United States
- CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
- CCOP - Carle Cancer Center — Urbana, Illinois, United States
- Indiana University Cancer Center — Indianapolis, Indiana, United States
- CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
- CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
- CCOP - Kalamazoo — Kalamazoo, Michigan, United States
- CCOP - Duluth — Duluth, Minnesota, United States
- University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
- CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
- CCOP - Missouri Valley Cancer Consortium — Omaha, Nebraska, United States
- CCOP - Northern New Jersey — Hackensack, New Jersey, United States
- Ireland Cancer Center — Cleveland, Ohio, United States
- CCOP - Toledo Community Hospital Oncology Program — Toledo, Ohio, United States
- CCOP - Sooner State — Tulsa, Oklahoma, United States
- Veterans Affairs Medical Center - Nashville — Nashville, Tennessee, United States
- Vanderbilt Cancer Center — Nashville, Tennessee, United States
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States
- Veterans Affairs Medical Center - Milwaukee (Zablocki) — Milwaukee, Wisconsin, United States
- Pretoria Academic Hospital — Pretoria, South Africa
Full record on ClinicalTrials.gov
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