SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant
Completed · Phase 2
Conditions studied: Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
In brief
RATIONALE: Reducing the amount of drugs used to prevent transplant rejection may help a person's body kill tumor cells. Giving biological therapy, such as interferon alfa, which may interfere with the growth of cancer cells, or combination chemotherapy, which uses different ways to stop tumor cells from dividing so they stop growing or die, may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of reducing immunosuppression, and giving interferon alfa and combination chemotherapy, in treating patients who have malignant tumors that develop after organ transplant.
Key facts
- Study ID
- NCT00002657
- Run by
- SWOG Cancer Research Network
- People needed
- 20
- Starts
- 1995-05-01
- Expected to finish
- 2011-07-01
- Last updated by the study team
- 2013-01-24
Who can join
Age: 15 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- CCOP - Greater Phoenix — Phoenix, Arizona, United States
- Veterans Affairs Medical Center - Phoenix (Hayden) — Phoenix, Arizona, United States
- Veterans Affairs Medical Center - Tucson — Tucson, Arizona, United States
- Arizona Cancer Center — Tucson, Arizona, United States
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Veterans Affairs Medical Center - Little Rock (McClellan) — Little Rock, Arkansas, United States
- Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
- USC/Norris Comprehensive Cancer Center — Los Angeles, California, United States
- Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
- Beckman Research Institute, City of Hope — Los Angeles, California, United States
- Veterans Affairs Outpatient Clinic - Martinez — Martinez, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- University of California Davis Medical Center — Sacramento, California, United States
- CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
- David Grant Medical Center — Travis Air Force Base, California, United States
- Veterans Affairs Medical Center - Denver — Denver, Colorado, United States
- University of Colorado Cancer Center — Denver, Colorado, United States
- CCOP - Atlanta Regional — Atlanta, Georgia, United States
- Cancer Research Center of Hawaii — Honolulu, Hawaii, United States
- CCOP - Central Illinois — Decatur, Illinois, United States
- Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital) — Hines, Illinois, United States
- Loyola University Medical Center — Maywood, Illinois, United States
- University of Kansas Medical Center — Kansas City, Kansas, United States
- CCOP - Wichita — Wichita, Kansas, United States
- MBCCOP - University of South Alabama — Mobile, Alabama, United States
Full record on ClinicalTrials.gov
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