Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Cancer of the Esophagus

Completed · Phase 3

Conditions studied: Esophageal Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not known whether high-dose radiation therapy is more effective than standard dose radiation therapy in treating cancer of the esophagus. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy plus high- or standard-dose radiation therapy in treating patients with cancer of the esophagus.

Key facts

Study ID

NCT00002631

Run by

Radiation Therapy Oncology Group

People needed

298

Starts

1995-06-01

Last updated by the study team

2013-11-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• CCOP - Scottsdale Oncology Program — Scottsdale, Arizona, United States
• CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
• CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
• Siouxland Hematology-Oncology — Sioux City, Iowa, United States
• CCOP - Wichita — Wichita, Kansas, United States
• CCOP - Duluth — Duluth, Minnesota, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• CentraCare Clinic — Saint Cloud, Minnesota, United States
• Quain & Ramstad Clinic, P.C. — Bismarck, North Dakota, United States
• CCOP - Merit Care Hospital — Fargo, North Dakota, United States
• Altru Health Systems — Grand Forks, North Dakota, United States
• CCOP - Toledo Community Hospital Oncology Program — Toledo, Ohio, United States
• CCOP - Geisinger Clinical and Medical Center — Danville, Pennsylvania, United States
• Rapid City Regional Hospital — Rapid City, South Dakota, United States
• CCOP - Sioux Community Cancer Consortium — Sioux Falls, South Dakota, United States
• Saskatchewan Cancer Agency — Regina, Saskatchewan, Canada

Full record on ClinicalTrials.gov

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