Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors
Completed · Phase 2
Conditions studied: Brain Tumor, Central Nervous System Tumor
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so that they stop growing or die. bone marrow transplantation and peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by bone marrow transplantation and/or peripheral stem cell transplantation in treating patients who have recurrent medulloblastoma or CNS germ cell tumors.
Key facts
- Study ID
- NCT00002594
- Run by
- Children's Oncology Group
- People needed
- 31
- Starts
- 1994-09-01
- Expected to finish
- 2007-03-01
- Last updated by the study team
- 2014-07-24
Who can join
Age: 2 and older, up to 25. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of South Alabama Medical Center — Mobile, Alabama, United States
- Arizona Cancer Center — Tucson, Arizona, United States
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Sutter Cancer Center — Sacramento, California, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego — San Diego, California, United States
- Children's Hospital San Diego — San Diego, California, United States
- Kaiser Permanente Medical Center - Santa Clara — Santa Clara, California, United States
- Stanford University Medical Center — Stanford, California, United States
- Yale Comprehensive Cancer Center — New Haven, Connecticut, United States
- Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
- Broward General Medical Center — Fort Lauderdale, Florida, United States
- Children's Hospital of Southwest Florida — Fort Myers, Florida, United States
- Shands Hospital and Clinics, University of Florida — Gainesville, Florida, United States
- Joe DiMaggio Children's Hospital at Memorial — Hollywood, Florida, United States
- Nemours Children's Clinic — Jacksonville, Florida, United States
- Sylvester Cancer Center, University of Miami — Miami, Florida, United States
- Miami Children's Hospital — Miami, Florida, United States
- Baptist Hospital of Miami — Miami, Florida, United States
- Florida Hospital Cancer Institute — Orlando, Florida, United States
- Nemours Children's Clinic-Orlando — Orlando, Florida, United States
- Sacred Heart Children's Hospital — Pensacola, Florida, United States
- All Children's Hospital — St. Petersburg, Florida, United States
- University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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